Jump to content

Paul Tsang

The neutral encyclopedia of notable people
Paul Tsang
NationalityAmerican
OccupationProfessor, reproductive biologist
Known forResearch on steroidogenesis in bovine luteal cells and elasmobranch reproductive endocrinology

Paul Tsang is a professor at the University of New Hampshire in Durham, New Hampshire, where his research addresses reproductive endocrinology in domestic and marine animal species.[1] Over several decades he has produced a body of work examining hormone regulation in bovine ovarian cells and reproductive assessment methods for elasmobranch fishes, contributing findings that have been cited in scientific literature more than 1,500 times.[2] His publication record spans 58 papers with an h-index of 21, reflecting sustained output across topics in cellular signaling, steroid biosynthesis, and animal health.[3]

Education

Specific details regarding Paul Tsang's undergraduate and graduate education are not documented in available public records.[4] His subsequent academic appointment and research specialization in reproductive biology and endocrinology indicate advanced training in animal science, physiology, or a related biomedical discipline, consistent with the doctoral-level expertise typically required for faculty positions in these fields at research universities.[5]

Career

Paul Tsang holds a faculty position at the University of New Hampshire in Durham, where he has been affiliated with programs in animal and reproductive biology.[6] Throughout his career, Tsang has directed research examining the cellular and molecular mechanisms underlying reproductive hormone production, with particular attention to the bovine ovary and the corpus luteum.[7]

In addition to his laboratory-based work on livestock reproductive physiology, Tsang has collaborated on research applying similar hormonal assessment techniques to wild and captive elasmobranch species, including sharks and rays.[8] This work extended methodologies developed for terrestrial livestock into conservation-oriented fisheries science, supporting efforts to monitor reproductive status in species subject to fishing pressure.[9]

His career has also included contributions to clinical and applied research outside of basic reproductive biology, such as studies on laboratory operations and oral health interventions among elderly populations, indicating a broad range of collaborative research interests beyond his core specialization.[10][11]

Research

Paul Tsang's research program has centered on the endocrinology of reproduction, with a particular focus on the regulation of steroid hormone biosynthesis in ovarian cells of cattle. A substantial portion of his published work investigates the corpus luteum, the transient endocrine structure that forms in the ovary following ovulation and is responsible for producing progesterone necessary to sustain pregnancy.[12]

Among his research themes is the role of cellular communication network factor 1 (CCN1), a matricellular protein implicated in cell signaling processes within the ovary. Tsang and collaborators examined how CCN1 expression is influenced by fetal bovine serum concentration in cultured granulosa cells, work that contributes to a broader understanding of how extracellular signals affect follicular cell function.[13] Related work explored the regulatory relationship between CCN1 and Ras homolog family member A (RhoA) in steroidogenic luteal cells, addressing intracellular signaling pathways that govern hormone-producing cell behavior.[14]

Tsang's laboratory has also investigated the Akt signaling pathway, a component of intracellular kinase cascades relevant to cell survival and hormone production, publishing methodological work on optimizing detection of phosphorylated Akt (pAkt) in bovine granulosa cells.[15] This methodological emphasis reflects an interest in refining laboratory techniques used broadly in reproductive cell biology research.

More recently, Tsang's work has extended to phytoestrogens, plant-derived compounds with estrogen-like activity, and their effects on progesterone biosynthesis in dairy cattle, an area of applied relevance to livestock nutrition and reproductive management.[16]

Beyond bovine reproductive biology, Tsang has contributed to research on matrilin-1, an extracellular matrix protein, and its function as an inhibitor of neovascularization, the formation of new blood vessels. This 2014 study, published in the Journal of Biological Chemistry, has become one of his more highly cited works, with 15 citations recorded, reflecting relevance to research on angiogenesis and tissue remodeling that intersects with reproductive tissue biology, including the transient vascularization events occurring in the corpus luteum.[17]

Tsang's research on elasmobranch reproductive endocrinology represents a distinct but methodologically related line of inquiry. In work examining spiny dogfish (Squalus acanthias), a shark species subject to substantial fishing pressure in the Western North Atlantic, Tsang and colleagues used a multi-parameter approach, incorporating measures beyond simple size-at-maturity estimates, to reassess maturity status in the population. This 2013 study has accumulated 19 citations and has been referenced in subsequent fisheries management and conservation literature.[18] Related work in the same year examined the use of steroid hormones extracted from skeletal muscle tissue, rather than blood plasma, as an alternative method for assessing reproductive status in elasmobranch fishes, a technique with practical value for field studies where live capture and blood sampling may be difficult or harmful to the animal.[19]

A 2018 study extended this line of work by examining how delays in blood processing, specifically delayed phlebotomy, affect measured plasma steroid hormone concentrations in two elasmobranch species, addressing a methodological concern relevant to field-based endocrine sampling in marine research settings.[20]

Tsang's research portfolio additionally includes applied studies outside his primary specialization, such as investigation into laboratory operations concerning blood collection tube supply chains, an area of relevance during periods of medical supply shortage, and a randomized trial assessing an ultrasonic denture hygiene intervention among community-dwelling elderly populations.[21][22] These publications suggest involvement in interdisciplinary or applied clinical research collaborations distinct from his core focus on reproductive endocrinology.

Recognition

Paul Tsang's research has been cited over 1,500 times across his body of published work, with an h-index of 21, indicating sustained influence within the fields of reproductive biology, animal science, and fisheries conservation.[23] His 2013 study on maturity assessment in spiny dogfish and his 2014 study on matrilin-1 as an inhibitor of neovascularization represent his most heavily cited individual works, at 19 and 15 citations respectively.[24][25] His work on elasmobranch reproductive assessment methods has informed subsequent conservation physiology research addressing sustainable fisheries management for shark and ray populations.[26]

Publications

  • Tsang, P. et al. "PSXIII-12 Effects of phytoestrogens on progesterone biosynthesis in dairy cows." Journal of Animal Science (2024).
  • Tsang, P. et al. "A randomized trial of the effectiveness of an ultrasonic denture hygiene intervention program among community dwelling elders." European Oral Research (2023).
  • Tsang, P. et al. "Regulation of cellular communication network factor 1 by Ras homolog family member A in bovine steroidogenic luteal cells." Journal of Animal Science (2022).
  • Tsang, P. et al. "Applying Best Practice to Converting Blood Collection Tube Suppliers: Overcoming Laboratory Supply Shortages." American Journal of Clinical Pathology (2021).
  • Tsang, P. et al. "Effects of Fetal Bovine Serum (FBS) Concentration on mRNA Expression of Cellular Communication Network Factor 1 (CCN1) in Bovine Granulosa Cells." (2020).
  • Tsang, P. et al. "Effects of delayed phlebotomy on plasma steroid hormone concentrations in two elasmobranch species." (2018).
  • Tsang, P. et al. "Optimization of pAkt Expression and Detection in Bovine Granulosa Cells." (2016).
  • Tsang, P. et al. "Matrilin-1 Is an Inhibitor of Neovascularization." Journal of Biological Chemistry (2014).
  • Tsang, P. et al. "Assessing reproductive status in elasmobranch fishes using steroid hormones extracted from skeletal muscle tissue." Conservation Physiology (2013).
  • Tsang, P. et al. "Using a multi-parameter approach to reassess maturity of spiny dogfish, Squalus acanthias, following increased fishing pressure in the Western North Atlantic." (2013).

<script type="application/ld+json"> { 

 "@context": "https://schema.org",
 "@type": "Person",
 "@id": "https://biography.wiki/a/Paul_Tsang#person",
 "name": "Paul Tsang",
 "affiliation": {
   "@type": "CollegeOrUniversity",
   "name": "University of New Hampshire",
   "address": "Durham, New Hampshire"
 },
 "jobTitle": "Professor",
 "knowsAbout": [
   "Reproductive endocrinology",
   "Bovine steroidogenesis",
   "Elasmobranch reproductive biology",
   "Cellular signaling"
 ]

} </script>

  1. ↑ University of New Hampshire faculty directory, Department of Molecular, Cellular, and Biomedical Sciences.
  2. ↑ Semantic Scholar author profile for Paul Tsang.
  3. ↑ Semantic Scholar author profile for Paul Tsang.
  4. ↑ No verifiable public record of educational history was located.
  5. ↑ University of New Hampshire faculty directory.
  6. ↑ University of New Hampshire faculty directory.
  7. ↑ Tsang, P. et al. "Regulation of cellular communication network factor 1 by Ras homolog family member A in bovine steroidogenic luteal cells." Journal of Animal Science (2022).
  8. ↑ Tsang, P. et al. "Assessing reproductive status in elasmobranch fishes using steroid hormones extracted from skeletal muscle tissue." Conservation Physiology (2013).
  9. ↑ Tsang, P. et al. "Using a multi-parameter approach to reassess maturity of spiny dogfish, Squalus acanthias, following increased fishing pressure in the Western North Atlantic." (2013).
  10. ↑ Tsang, P. et al. "Applying Best Practice to Converting Blood Collection Tube Suppliers: Overcoming Laboratory Supply Shortages." American Journal of Clinical Pathology (2021).
  11. ↑ Tsang, P. et al. "A randomized trial of the effectiveness of an ultrasonic denture hygiene intervention program among community dwelling elders." European Oral Research (2023).
  12. ↑ Tsang, P. et al. "Regulation of cellular communication network factor 1 by Ras homolog family member A in bovine steroidogenic luteal cells." Journal of Animal Science (2022).
  13. ↑ Tsang, P. et al. "Effects of Fetal Bovine Serum (FBS) Concentration on mRNA Expression of Cellular Communication Network Factor 1 (CCN1) in Bovine Granulosa Cells." Journal of Animal Science (2020).
  14. ↑ Tsang, P. et al. "Regulation of cellular communication network factor 1 by Ras homolog family member A in bovine steroidogenic luteal cells." Journal of Animal Science (2022).
  15. ↑ Tsang, P. et al. "Optimization of pAkt Expression and Detection in Bovine Granulosa Cells." (2016).
  16. ↑ Tsang, P. et al. "PSXIII-12 Effects of phytoestrogens on progesterone biosynthesis in dairy cows." Journal of Animal Science (2024).
  17. ↑ Tsang, P. et al. "Matrilin-1 Is an Inhibitor of Neovascularization." Journal of Biological Chemistry (2014).
  18. ↑ Tsang, P. et al. "Using a multi-parameter approach to reassess maturity of spiny dogfish, Squalus acanthias, following increased fishing pressure in the Western North Atlantic." (2013).
  19. ↑ Tsang, P. et al. "Assessing reproductive status in elasmobranch fishes using steroid hormones extracted from skeletal muscle tissue." Conservation Physiology (2013).
  20. ↑ Tsang, P. et al. "Effects of delayed phlebotomy on plasma steroid hormone concentrations in two elasmobranch species." (2018).
  21. ↑ Tsang, P. et al. "Applying Best Practice to Converting Blood Collection Tube Suppliers: Overcoming Laboratory Supply Shortages." American Journal of Clinical Pathology (2021).
  22. ↑ Tsang, P. et al. "A randomized trial of the effectiveness of an ultrasonic denture hygiene intervention program among community dwelling elders." European Oral Research (2023).
  23. ↑ Semantic Scholar author profile for Paul Tsang.
  24. ↑ Tsang, P. et al. "Using a multi-parameter approach to reassess maturity of spiny dogfish, Squalus acanthias, following increased fishing pressure in the Western North Atlantic." (2013).
  25. ↑ Tsang, P. et al. "Matrilin-1 Is an Inhibitor of Neovascularization." Journal of Biological Chemistry (2014).
  26. ↑ Tsang, P. et al. "Assessing reproductive status in elasmobranch fishes using steroid hormones extracted from skeletal muscle tissue." Conservation Physiology (2013).
Retrieved from "https://fullbios.com/index.php?title=Paul_Tsang&oldid=52641"